Pentoxifylline, a Methyl Xanthine Derivative, Reduces Peritoneal Adhesions and Increases Peritoneal Fibrinolysis in Rats
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چکیده
منابع مشابه
Effect of gold nanoparticles on postoperative peritoneal adhesions in rats
Objective(s): Abdominal adhesions are one of the most important problems, occurring after intra-abdominal surgery in more than 90% of cases. This condition is the leading cause of bowel obstruction, infertility, and abdominal/pelvic pain. Gold nanoparticles (GNPs) have been shown to be non-toxic and exhibit anti-inflammatory, anti-angiogenic and antioxidant activities. The purpose of this study...
متن کاملPeritoneal closure and adhesions.
We have read the debate on peritoneal closure by Cheong et al. with interest (Cheong et al., 2001). The authors state that the long term benefits and hazards of non-closure of the peritoneum are unknown, and expect adhesion related problems. Among the various outcome measures concerning long-term morbidity, adhesion formation/reformation is probably one of the most important ones. The presence ...
متن کاملeffect of gold nanoparticles on postoperative peritoneal adhesions in rats
objective(s): abdominal adhesions are one of the most important problems, occurring after intra-abdominal surgery in more than 90% of cases. this condition is the leading cause of bowel obstruction, infertility, and abdominal/pelvic pain. gold nanoparticles (gnps) have been shown to be non-toxic and exhibit anti-inflammatory, anti-angiogenic and antioxidant activities. the purpose of this study...
متن کاملAllopurinol reduces the severity of peritoneal adhesions in mice.
A study was designed to investigate the possibility of reducing peritoneal adhesion formation in mice by pretreatment with allopurinol. Allopurinol, at a dose of 35 mg/kg of body weight/d significantly reduced the severity of peritoneal adhesions (P < .001), and also the neutrophil response to ischemia (P < .05). Tissue myeloperoxidase activity at the site of ischemic injury was significantly l...
متن کاملMast cells in peritoneal fluid in rats with experimentally induced peritoneal adhesions.
Mast cells (MC) produce, store and release many biologically active substances, especially inflammatory factors, chemotactic substances for neutrophiles, cytokines and prostaglandins. They play very important role in fibrinosis and they are an important factor in peritoneal adhesions formation and lysis. In this study we tried to evaluate role of mast cells in peritoneal adhesions formation. We...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 2006
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.209.249